Approximately 50% to 60% of amyotrophic lateral sclerosis (ALS) is characterized by an increase in metabolic rate. The Harris and Benedict (HB) 1919 formula is the equation mainly used to calculate resting energy expenditure (cREE) compared with measured REE (mREE) by indirect calorimetry (IC), but other formulas are also applied in current practice.
The present study aimed to assess mREE in patients with ALS compared with 12 cREE formulas and study the relevant threshold of REE variation to screen patients with a higher evolving risk.Nutritional assessments and body composition (by bioimpedance analysis) were performed in patients with ALS.
mREE was measured by IC, and cREE was calculated using the HB 1919, HB 1984, World Schofield, De Lorenzo, Johnstone, Mifflin, World Health Organization/FoodandAgricultureOrganization, Owen, Fleisch, Wang, Rosenbaum, and Nelson formulas.
Functional and respiratory evolution and survival by log-rank test according to two thresholds of REE variation (10% and 20%) were studied.A total of 315 patients with ALS were included in the study. The median mREE was 1503 kcal/24 h (range, 1290-1698 kcal/24 h), which was higher than all predictive equations (P < 0.0001). Depending on the predictive equation, REE variation >10% and 20% was found in 35.2% to 76.3% and 14.6% to 53.3% of patients with ALS, respectively.
Patients with an REE variation >20% with HB 1919 and HB 1984 had a lower survival. Moreover, with this same threshold and the Mifflin formula, patients had higher functional and respiratory evolutions and lower survival.The increase in metabolic rate is present according to the different cREE formulas used compared with IC.
In clinical practice, REE formulas (e.g., HB 1919, HB 1984, or Mifflin) can be used as a reference value compared with IC to screen patients with ALS with an REE variation >20% and a higher evolving risk.
Compound FL0097 |
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FL0097-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Compound FL0097 |
Julabo FL1201 Chiller - EACH |
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BAT2504 | Scientific Laboratory Supplies | EACH | EUR 9028.8 |
FL411 |
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462472 | MedKoo Biosciences | 25.0mg | EUR 450 |
(R)-FL-118 |
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F401290 | Toronto Research Chemicals | 25mg | EUR 23000 |
Description: 151636-76-9 |
FL-118 |
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MBS130803-100mg | MyBiosource | 100mg | EUR 1065 |
FL-118 |
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MBS130803-500mg | MyBiosource | 500mg | EUR 2775 |
FL-411 |
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HY-111102 | MedChemExpress | 25mg | EUR 1575.6 |
FL104 |
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T27328-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: FL104 |
FL104 |
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T27328-1g | TargetMol Chemicals | 1g | Ask for price |
Description: FL104 |
FL104 |
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T27328-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: FL104 |
FL104 |
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T27328-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: FL104 |
FL104 |
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T27328-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: FL104 |
FL118 |
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T27329-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: FL118 |
FL118 |
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T27329-1g | TargetMol Chemicals | 1g | Ask for price |
Description: FL118 |
FL118 |
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T27329-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: FL118 |
FL118 |
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T27329-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: FL118 |
FL118 |
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T27329-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: FL118 |
FL-411 |
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T4365-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: FL-411 |
FL-411 |
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T4365-1g | TargetMol Chemicals | 1g | Ask for price |
Description: FL-411 |
FL-411 |
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T4365-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: FL-411 |
FL-411 |
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T4365-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: FL-411 |
FL-411 |
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T4365-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: FL-411 |
FL104 |
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MBS5777039-5mg | MyBiosource | 5(mg | EUR 915 |
FL104 |
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MBS5777039-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
FL118 |
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MBS5777040-5mg | MyBiosource | 5(mg | EUR 915 |
FL118 |
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MBS5777040-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
FL-411 |
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MBS3843961-100mg | MyBiosource | 100mg | EUR 3755 |
FL-411 |
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MBS3843961-10mg | MyBiosource | 10mg | EUR 685 |
FL-411 |
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MBS3843961-50mg | MyBiosource | 50mg | EUR 1915 |
FL-411 |
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MBS3843961-5mg | MyBiosource | 5mg | EUR 425 |
FL-411 |
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MBS3843961-5x100mg | MyBiosource | 5x100mg | EUR 16900 |
FL-411 |
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MBS3603371-10mg | MyBiosource | 10mg | EUR 585 |
FL-411 |
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MBS3603371-2mg | MyBiosource | 2mg | EUR 310 |
FL-411 |
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MBS3603371-5mg | MyBiosource | 5mg | EUR 415 |
FL-411 |
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MBS3603371-5x10mg | MyBiosource | 5x10mg | EUR 2300 |
FL-411 |
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MBS5750496-10mg | MyBiosource | 10mg | EUR 455 |
FL-411 |
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MBS5750496-1mg | MyBiosource | 1mg | EUR 210 |
FL-411 |
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MBS5750496-25mg | MyBiosource | 25mg | EUR 825 |
FL-411 |
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MBS5750496-2mg | MyBiosource | 2mg | EUR 255 |
FL-411 |
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MBS5750496-5mg | MyBiosource | 5mg | EUR 305 |
Human IL-37(1F7/F1L1ζ) ELISA kit |
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E22-HC116.48 | EnoGene | 48T | EUR 295 |
Human IL-37(1F7/F1L1ζ) ELISA kit |
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E22-HC116.96 | EnoGene | 96T | EUR 395 |
Julabo FL300 Chiller - EACH |
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BAT2500 | Scientific Laboratory Supplies | EACH | EUR 5287.95 |
Julabo FL601 Chiller - EACH |
|||
BAT2502 | Scientific Laboratory Supplies | EACH | EUR 7109.1 |
p53 (FL-393) Antibody HRP Conjugated |
|||
MBS9461916-01mL | MyBiosource | 0.1mL | EUR 595 |
p53 (FL-393) Antibody HRP Conjugated |
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MBS9461916-5x01mL | MyBiosource | 5x0.1mL | EUR 2525 |
FL83B |
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CSC-C7105J | Creative Bioarray | One Frozen vial | Ask for price |
Description: Embryonic Liver Spontaneously immortalized cell line |
F630111L10Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each |
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SR401571 | Origene Technologies GmbH | 2 nmol | Ask for price |
BSA (FL11) Antibody |
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MBS440112-02mg | MyBiosource | 0.2mg | EUR 285 |
BSA (FL11) Antibody |
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MBS440112-5x02mg | MyBiosource | 5x0.2mg | EUR 1185 |
Anti-ORF1 FL49 (4E11) |
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YF-MA19548 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to ORF1 FL49 |
BSA (FL11)+HRP Antibody |
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MBS440113-02mg | MyBiosource | 0.2mg | EUR 350 |
BSA (FL11)+HRP Antibody |
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MBS440113-5x02mg | MyBiosource | 5x0.2mg | EUR 1480 |
BSA (FL11)+FITC Antibody |
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MBS440114-02mg | MyBiosource | 0.2mg | EUR 350 |
BSA (FL11)+FITC Antibody |
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MBS440114-5x02mg | MyBiosource | 5x0.2mg | EUR 1480 |
Human IL-37/IL1F7/F1L1Z ELISA Kit |
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RK00117 | Abclonal | 96 Tests | EUR 280 |
Human IL-37/IL1F7/F1L1Z ELISA Kit |
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MBS9135824-5x96Tests | MyBiosource | 5x96Tests | EUR 2615 |
Human IL-37/IL1F7/F1L1Z ELISA Kit |
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MBS9135824-96Tests | MyBiosource | 96Tests | EUR 570 |
Human IL-37 (1F7/F1L1zeta) ELISA Kit |
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MBS8579181-48Tests | MyBiosource | 48Tests | EUR 390 |
Human IL-37 (1F7/F1L1zeta) ELISA Kit |
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MBS8579181-5x96Tests | MyBiosource | 5x96Tests | EUR 2275 |
Human IL-37 (1F7/F1L1zeta) ELISA Kit |
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MBS8579181-96Tests | MyBiosource | 96Tests | EUR 495 |
Gilson PIPETMAN L Fixed F5000L 5000ul - EACH |
|||
FA10031 | Scientific Laboratory Supplies | EACH | EUR 288.9 |
ORF1 FL49 (CYSTM1) (NM_032412) Human Over-expression Lysate |
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LS084418 | BosterBio | 100ug | EUR 628 |
Description: Transient overexpression lysate of chromosome 5 open reading frame 32 (C5orf32) |
[Tyr10]-F2L (1-21) / [Tyr10]-HBP (1-21) (Rat, Mouse) |
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072-36 | PHOENIX PEPTIDE | 100 μg | EUR 160.92 |
2-Fluorobiphenyl (2-Fluoro-1,1'-biphenyl, 2-Fluorodiphenyl,) |
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MBS6114032-10g | MyBiosource | 10(g | EUR 555 |
2-Fluorobiphenyl (2-Fluoro-1,1'-biphenyl, 2-Fluorodiphenyl,) |
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MBS6114032-25g | MyBiosource | 25g | EUR 935 |
2-Fluorobiphenyl (2-Fluoro-1,1'-biphenyl, 2-Fluorodiphenyl,) |
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MBS6114032-5x25g | MyBiosource | 5x25g | EUR 4050 |
F2L (7-21) / HBP (7-21) (Human, Rat, Mouse, Porcine, Canine) |
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072-31 | PHOENIX PEPTIDE | 100 μg | EUR 160.92 |
[Tyr10]-F2L (1-21) / [Tyr10]-HBP (1-21) (Rat, Mouse) - I-125 Labeled |
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T-072-36 | PHOENIX PEPTIDE | 10 μCi | EUR 1145.88 |
Monkeypox Virus F3L (MPXV F3L) Protein |
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abx620121-100g | Abbexa | 100 µg | EUR 350 |
Monkeypox Virus F3L (MPXV F3L) Protein |
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abx620121-1mg | Abbexa | 1 mg | Ask for price |
Monkeypox Virus F3L (MPXV F3L) Protein |
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abx620121-200g | Abbexa | 200 µg | EUR 1350 |
[Tyr10]-F2L (1-21) / [Tyr10]-HBP (1-21) (Human, Canine, Porcine) |
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072-35 | PHOENIX PEPTIDE | 100 μg | EUR 160.92 |
[Tyr10]-F2L (1-21) / [Tyr10]-HBP (1-21) (Human, Canine, Porcine) - I-125 Labeled |
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T-072-35 | PHOENIX PEPTIDE | 10 μCi | EUR 1145.88 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) |
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072-34 | PHOENIX PEPTIDE | 100 μg | EUR 199.8 |
acetyl-[Tyr22]-F2L (1-21) / acetyl-[Tyr22]-HBP (1-21) (Human, Porcine, Canine) |
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072-63 | PHOENIX PEPTIDE | 100 μg | EUR 243 |
N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe |
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D292325 | Toronto Research Chemicals | 100mg | EUR 227 |
Description: 1700622-06-5 |
FL3 |
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T27330-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: FL3 |
FL3 |
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T27330-1g | TargetMol Chemicals | 1g | Ask for price |
Description: FL3 |
FL3 |
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T27330-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: FL3 |
FL3 |
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T27330-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: FL3 |
FL3 |
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T27330-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: FL3 |
FL3 |
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MBS5777041-5mg | MyBiosource | 5(mg | EUR 915 |
FL3 |
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MBS5777041-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
N-Des(4-Fluorophenyl)-N-(3-Fluorophenyl)-Ezetimibe-d4 |
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D292327 | Toronto Research Chemicals | 50mg | EUR 7600 |
4-Fluoro-delta-(4-fluorophenyl)benzenebutanol |
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F591810 | Toronto Research Chemicals | 2.5g | EUR 3000 |
Description: 50337-85-4 |
3-(3-Fluorobenzyl)-4-[(3-fluorobenzyl)oxy]benzaldehyde |
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F597935 | Toronto Research Chemicals | 10mg | EUR 345 |
Description: 1000370-24-0 |
3-(2-Fluorobenzyl)-4-[(2-fluorobenzyl)oxy]benzaldehyde |
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F597955 | Toronto Research Chemicals | 500mg | EUR 800 |
Description: 1000370-25-1 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - Antibody |
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H-072-34 | PHOENIX PEPTIDE | 100 μl | EUR 666.36 |
3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) Aprepitant |
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D228795 | Toronto Research Chemicals | 75mg | EUR 12800 |
1-(4-Fluorophenyl)-N-[(4-fluorophenyl)methyl]methanimine |
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F632245 | Toronto Research Chemicals | 250mg | EUR 1200 |
Description: 428819-12-9 |
acetyl-[Tyr22]-F2L (1-21) / acetyl-[Tyr22]-HBP (1-21) (Human, Porcine, Canine) - I-125 Labeled |
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T-072-63 | PHOENIX PEPTIDE | 10 μCi | EUR 1145.88 |
4-Fluoro-7-azaindole (4-Fluoro-1H-pyrrolo[2,3-b]pyridine) |
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MBS6094472-100mg | MyBiosource | 100(mg | EUR 610 |
4-Fluoro-7-azaindole (4-Fluoro-1H-pyrrolo[2,3-b]pyridine) |
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MBS6094472-5x100mg | MyBiosource | 5x100mg | EUR 2600 |
5-Fluoro-2-oxindole (5-Fluoro-1,3-dihydro-indol-2-one,) |
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MBS6021997-1g | MyBiosource | 1(g | EUR 440 |
5-Fluoro-2-oxindole (5-Fluoro-1,3-dihydro-indol-2-one,) |
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MBS6021997-5x1g | MyBiosource | 5x1g | EUR 1825 |
5-Fluoro-2-(4-fluorophenyl)-4-(trifluoromethyl)-1,3-oxazole |
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F601165 | Toronto Research Chemicals | 100mg | EUR 1200 |
Description: 83081-29-2 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Human, Porcine, Canine) |
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072-30 | PHOENIX PEPTIDE | 100 μg | EUR 199.8 |
(S)-2-[[3-(3-Fluorobenzyl)-4-[(3-fluorobenzyl)oxy]benzyl]amino]propanamide |
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F590975 | Toronto Research Chemicals | 10mg | EUR 775 |
Description: 1000370-27-3 |
4-Fluoro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde |
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F428220 | Toronto Research Chemicals | 500mg | EUR 800 |
Description: 928324-57-6 |
5-fluoro 203 |
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C4114-10 | ApexBio | 10 mg | EUR 154 |
Description: AhR signaling activator |
5-fluoro 203 |
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C4114-25 | ApexBio | 25 mg | EUR 348 |
Description: AhR signaling activator |
5-fluoro 203 |
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C4114-5 | ApexBio | 5 mg | EUR 83 |
Description: AhR signaling activator |
5-fluoro 203 |
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T21704-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: 5-fluoro 203 |
5-fluoro 203 |
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T21704-1g | TargetMol Chemicals | 1g | Ask for price |
Description: 5-fluoro 203 |
5-fluoro 203 |
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T21704-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: 5-fluoro 203 |
5-fluoro 203 |
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T21704-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: 5-fluoro 203 |
5-fluoro 203 |
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T21704-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: 5-fluoro 203 |
5-fluoro 203 |
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MBS5764812-10mg | MyBiosource | 10mg | EUR 285 |
5-fluoro 203 |
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MBS5764812-25mg | MyBiosource | 25mg | EUR 555 |
5-fluoro 203 |
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MBS5764812-2mg | MyBiosource | 2mg | EUR 155 |
5-fluoro 203 |
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MBS5764812-50mg | MyBiosource | 50mg | EUR 745 |
5-fluoro 203 |
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MBS5764812-5mg | MyBiosource | 5mg | EUR 210 |
4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl |
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T50103-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl]sulfamoyl}benzamide |
4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl |
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T50103-1g | TargetMol Chemicals | 1g | Ask for price |
Description: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl]sulfamoyl}benzamide |
4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl |
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T50103-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl]sulfamoyl}benzamide |
4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl |
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T50103-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl]sulfamoyl}benzamide |
4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl |
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T50103-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-{[(4-methoxyphenyl)methyl]sulfamoyl}benzamide |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - Cy5 Labeled Purified IgG |
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FC5-G-072-34 | PHOENIX PEPTIDE | 100 μl | EUR 1102.68 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - FAM Labeled Purified IgG |
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FG-G-072-34A | PHOENIX PEPTIDE | 100 μl | EUR 666.36 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - Purified IgG Antibody |
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G-072-34 | PHOENIX PEPTIDE | 200 μg | EUR 666.36 |
5-Fluoro ADB |
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F587245 | Toronto Research Chemicals | 10mg | EUR 158 |
Description: 1971007-89-2 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Human, Porcine, Canine) - Antibody |
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H-072-30 | PHOENIX PEPTIDE | 100 μl | EUR 666.36 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - I-125 Labeled Purified IgG |
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T-G-072-34 | PHOENIX PEPTIDE | 10 μCi | EUR 1145.88 |
5-fluoro AMT HCl |
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463460 | MedKoo Biosciences | 1.0mg | EUR 350 |
5-Fluoro NNEI |
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F588720 | Toronto Research Chemicals | 10mg | EUR 759 |
Description: 1445580-60-8 |
pCDNA3.1-FLAG(-) |
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PVT18203 | Nova Lifetech | 2ug | EUR 162 |
(4-Fluoro-1-naphthalenyl)[1-(5-fluoropentyl)-1H-indol-3-yl]methanone |
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F594460 | Toronto Research Chemicals | 50mg | EUR 1800 |
Description: 1391485-39-4 |
F2L (1-21), nonacetylated / HBP (1-21), nonacetylated (Rat, Mouse) - Biotin Labeled Purified IgG |
|||
B-G-072-34 | PHOENIX PEPTIDE | 100 μl | EUR 666.36 |
5-Fluoro-AMB |
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F587305 | Toronto Research Chemicals | 100mg | EUR 1800 |
Description: 1801552-03-3 |
9-Fluorenol 95% |
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F01640 | Pfaltz & Bauer | 5G | EUR 106.51 |
5-Fluoro-UTP |
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NU-1115L | Jena Bioscience GmbH | 5 x 10µl | EUR 461.7 |
5-Fluoro-UTP |
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NU-1115S | Jena Bioscience GmbH | 10µl | EUR 157.6 |
2-Fluoro-ATP |
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NU-145L | Jena Bioscience GmbH | 5 x 10µl | EUR 604.6 |
2-Fluoro-ATP |
|||
NU-145S | Jena Bioscience GmbH | 10µl | EUR 208.5 |
5-Fluoro-UMP |
|||
NU-146L | Jena Bioscience GmbH | 5 x 50µl | EUR 439.5 |
5-Fluoro-UMP |
|||
NU-146S | Jena Bioscience GmbH | 50µl | EUR 150.1 |
2-Fluoro-ADP |
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T29348-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: 2-Fluoro-ADP |
2-Fluoro-ADP |
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T29348-1g | TargetMol Chemicals | 1g | Ask for price |
Description: 2-Fluoro-ADP |
2-Fluoro-ADP |
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T29348-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: 2-Fluoro-ADP |
2-Fluoro-ADP |
|||
T29348-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: 2-Fluoro-ADP |
2-Fluoro-ADP |
|||
T29348-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: 2-Fluoro-ADP |
9-FLUORENOL |
|||
T8633-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: 9-FLUORENOL |
9-FLUORENOL |
|||
T8633-1g | TargetMol Chemicals | 1g | Ask for price |
Description: 9-FLUORENOL |
9-FLUORENOL |
|||
T8633-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: 9-FLUORENOL |
9-FLUORENOL |
|||
T8633-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: 9-FLUORENOL |
9-FLUORENOL |
|||
T8633-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: 9-FLUORENOL |
2-Fluoro-ADP |
|||
MBS5778987-5mg | MyBiosource | 5(mg | EUR 915 |
2-Fluoro-ADP |
|||
MBS5778987-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
GST (FL1) Antibody |
|||
MBS440075-02mg | MyBiosource | 0.2mg | EUR 285 |
GST (FL1) Antibody |
|||
MBS440075-5x02mg | MyBiosource | 5x0.2mg | EUR 1185 |
GFP (FL3) Antibody |
|||
MBS440077-01mg | MyBiosource | 0.1mg | EUR 350 |
One Health refers to the collaborative efforts of multiple disciplines working locally, nationally and globally to attain optimal health for people, animals and our environment.
The One Health approach is increasingly popular in the context of growing threats from emerging zoonoses, antimicrobial resistance and climate change.
The Food and Agriculture Organization of the United Nations, World Organisation for Animal Health and World Health Organization have been working together in the wake of the avian influenza crisis in the Asia-Pacific region to provide strong leadership to endorse the One Health concept and promote interagency and intersectoral collaboration.
The programme on highly pathogenic emerging diseases in Asia (2009-2014) led to the establishment of a regional tripartite coordination mechanism in the Asia-Pacific region to support collaboration between the animal and human health sectors. The remit of this mechanism has expanded to include other priority One Health challenges, such as antimicrobial resistance and food safety.
The mechanism has helped to organize eight Asia-Pacific workshops on multisectoral collaboration for the prevention and control of zoonoses since 2010, facilitating advocacy and operationalization of One Health at regional and country levels.
The tripartite group and international partners have developed several One Health tools, which are useful for operationalization of One Health at the country level. Member States are encouraged to develop a One Health strategic framework taking into account the country’s context and priorities.